South America

South America is huge, with scenic wonders that would impress even the most jaded traveler, cosmopolitan cities and native villages, snow-capped mountains, deserts and lush rain forests, miles of sandy beaches and areas so isolated a visitor feels swept back in time.

There are many options to cruising South America, and there is no better way to explore this vast continent than on a cruise vacation.

6 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Magnifica
Ports of Call: Santos (Sao Paulo), Brazil | Punta del Este, Uruguay | Buenos Aires, Argentina | Montevideo, Uruguay
MSC Magnifica

6 NIGHT SOUTH AMERICA CRUISE departing from Rio de Janeiro, Brazil

MSC Cruises
MSC Musica
Ports of Call: Rio de Janeiro, Brazil | Buzios, Brazil | Salvador, Brazil | Ilheus(Bahia), Brazil
MSC Musica

6 NIGHT SOUTH AMERICA CRUISE departing from Rio de Janeiro, Brazil

MSC Cruises
MSC Musica
Ports of Call: Rio de Janeiro, Brazil | Salvador, Brazil | Ilheus(Bahia), Brazil
MSC Musica

6 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Preziosa
Ports of Call: Santos (Sao Paulo), Brazil | Buzios, Brazil | Salvador, Brazil | Ilha Grande, Brazil
MSC Preziosa

7 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Magnifica
Ports of Call: Santos (Sao Paulo), Brazil | Montevideo, Uruguay | Buenos Aires, Argentina | Punta del Este, Uruguay
MSC Magnifica

7 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Magnifica
Ports of Call: Santos (Sao Paulo), Brazil | Punta del Este, Uruguay | Montevideo, Uruguay | Buenos Aires, Argentina
MSC Magnifica

7 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Magnifica
Ports of Call: Santos (Sao Paulo), Brazil | Punta del Este, Uruguay | Buenos Aires, Argentina | Montevideo, Uruguay
MSC Magnifica

7 NIGHT SOUTH AMERICA CRUISE departing from Rio de Janeiro, Brazil

MSC Cruises
MSC Musica
Ports of Call: Rio de Janeiro, Brazil | Ilheus(Bahia), Brazil | Salvador, Brazil | Buzios, Brazil
MSC Musica

7 NIGHT SOUTH AMERICA CRUISE departing from Rio de Janeiro, Brazil

MSC Cruises
MSC Musica
Ports of Call: Rio de Janeiro, Brazil | Cabo Frio, Brazil | Copacabana Beach, Brazil | Salvador, Brazil | Ilheus(Bahia), Brazil
MSC Musica

7 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Preziosa
Ports of Call: Santos (Sao Paulo), Brazil | Buzios, Brazil | Salvador, Brazil | Ilheus(Bahia), Brazil | Ilha Grande, Brazil
MSC Preziosa

7 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Preziosa
Ports of Call: Santos (Sao Paulo), Brazil | Salvador, Brazil | Ilheus(Bahia), Brazil | Ilha Grande, Brazil
MSC Preziosa

8 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Magnifica
Ports of Call: Santos (Sao Paulo), Brazil | Punta del Este, Uruguay | Buenos Aires, Argentina | Montevideo, Uruguay
MSC Magnifica

8 NIGHT SOUTH AMERICA CRUISE departing from Rio de Janeiro, Brazil

MSC Cruises
MSC Musica
Ports of Call: Rio de Janeiro, Brazil | Buenos Aires, Argentina | Punta del Este, Uruguay | Ilhabela, Brazil
MSC Musica

8 NIGHT SOUTH AMERICA CRUISE departing from Rio de Janeiro, Brazil

MSC Cruises
MSC Musica
Ports of Call: Rio de Janeiro, Brazil | Ilhabela, Brazil | Punta del Este, Uruguay | Buenos Aires, Argentina
MSC Musica

8 NIGHT SOUTH AMERICA CRUISE departing from Buenos Aires, Argentina

MSC Cruises
MSC Poesia
Ports of Call: Buenos Aires, Argentina | Punta del Este, Uruguay | Ilhabela, Brazil | Rio de Janeiro, Brazil | Ilha Grande, Brazil
MSC Poesia

8 NIGHT SOUTH AMERICA CRUISE departing from Buenos Aires, Argentina

MSC Cruises
MSC Poesia
Ports of Call: Buenos Aires, Argentina | Rio de Janeiro, Brazil | Ilha Grande, Brazil | Ilhabela, Brazil | Punta del Este, Uruguay
MSC Poesia

8 NIGHT SOUTH AMERICA CRUISE departing from Santos (Sao Paulo), Brazil

MSC Cruises
MSC Preziosa
Ports of Call: Santos (Sao Paulo), Brazil | Ilhabela, Brazil | Copacabana Beach, Brazil | Buzios, Brazil | Salvador, Brazil | Cabo Frio, Brazil
MSC Preziosa

9 NIGHT SOUTH AMERICA CRUISE departing from Buenos Aires, Argentina

MSC Cruises
MSC Poesia
Ports of Call: Buenos Aires, Argentina | Punta del Este, Uruguay | Copacabana Beach, Brazil | Rio de Janeiro, Brazil | Cabo Frio, Brazil | Ilha Grande, Brazil
MSC Poesia

9 NIGHT SOUTH AMERICA CRUISE departing from Buenos Aires, Argentina

MSC Cruises
MSC Poesia
Ports of Call: Buenos Aires, Argentina | Punta del Este, Uruguay | Ilhabela, Brazil | Rio de Janeiro, Brazil | Buzios, Brazil | Ilha Grande, Brazil
MSC Poesia

9 NIGHT SOUTH AMERICA CRUISE departing from Buenos Aires, Argentina

MSC Cruises
MSC Poesia
Ports of Call: Buenos Aires, Argentina | Punta del Este, Uruguay | Ilhabela, Brazil | Rio de Janeiro, Brazil | Cabo Frio, Brazil | Ilha Grande, Brazil
MSC Poesia

9 NIGHT SOUTH AMERICA CRUISE departing from Buenos Aires, Argentina

MSC Cruises
MSC Poesia
Ports of Call: Buenos Aires, Argentina | Rio de Janeiro, Brazil | Buzios, Brazil | Ilhabela, Brazil | Punta del Este, Uruguay
MSC Poesia

*From prices are per person, based on double occupancy and are cruise only unless otherwise specified. A 3.08% surcharge will apply for payments by Amex. A surcharge may apply for other card payments. Cruise guru charges a fee of $110 per person for cancellations and charges other fees in addition to any fees charged by cruise lines. Cancellation fees of up to 100% apply. View all fees and charges. Your exact price depends on the day of departure, departure city, ship and cabin. All offers and prices are for selected dates, sailings and cabin categories only and are subject to availability. Conditions apply.