South America

South America is huge, with scenic wonders that would impress even the most jaded traveler, cosmopolitan cities and native villages, snow-capped mountains, deserts and lush rain forests, miles of sandy beaches and areas so isolated a visitor feels swept back in time.

There are many options to cruising South America, and there is no better way to explore this vast continent than on a cruise vacation.

12-day Colors Of Brazil departing from Buenos Aires, Argentina

Holland America Line
Zaandam
Ports of Call: Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil | Buzios, Brazil | Abraao, Ilha Grande, Brazil | Santos (Sao Paulo), Brazil | Porto Belo (Santa Catarina), Brazil | Montevideo, Uruguay
Zaandam

13-day South America Passage departing from San Antonio, Chile

Holland America Line
Zaandam
Ports of Call: San Antonio, Chile | Puerto Montt, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Montevideo, Uruguay | Buenos Aires, Argentina
Zaandam

14-day Incan Empires departing from San Diego, California

Holland America Line
Maasdam
Ports of Call: San Diego, California | Cabo San Lucas, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Fuerte Amador, Panama | Salaverry (Trujillo), Peru | Callao (Lima), Peru
Maasdam

14-day Incan Empires departing from Callao (Lima), Peru

Holland America Line
Maasdam
Ports of Call: Callao (Lima), Peru | Manta (Quito), Ecuador | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Manzanillo, Mexico | Puerto Vallarta, Mexico | San Diego, California
Maasdam

14-day South America Passage departing from Buenos Aires, Argentina

Holland America Line
Zaandam
Ports of Call: Buenos Aires, Argentina | Montevideo, Uruguay | Stanley, Falkland Islands | Punta Arenas, Chile | Ushuaia, Argentina | Puerto Montt, Chile | San Antonio, Chile
Zaandam

14-day South America Passage departing from San Antonio, Chile

Holland America Line
Zaandam
Ports of Call: San Antonio, Chile | Puerto Montt, Chile | Puerto Chacabuco, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Montevideo, Uruguay | Buenos Aires, Argentina
Zaandam

15-day Incan Empires departing from San Diego, California

Holland America Line
Volendam
Ports of Call: San Diego, California | Cabo San Lucas, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru
Volendam

15-day Incan Empires departing from Callao (Lima), Peru

Holland America Line
Volendam
Ports of Call: Callao (Lima), Peru | General San Martin, Peru | Puntarenas, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Manzanillo, Mexico | Puerto Vallarta, Mexico | San Diego, California
Volendam

15-day South America Passage departing from Buenos Aires, Argentina

Holland America Line
Zaandam
Ports of Call: Buenos Aires, Argentina | Montevideo, Uruguay | Puerto Madryn, Argentina | Stanley, Falkland Islands | Punta Arenas, Chile | Ushuaia, Argentina | Puerto Montt, Chile | San Antonio, Chile
Zaandam

16-day Inca And Panama Canal Discovery departing from San Antonio, Chile

Holland America Line
Zaandam
Ports of Call: San Antonio, Chile | Coquimbo (La Serena), Chile | General San Martin, Peru | Callao (Lima), Peru | Salaverry (Trujillo), Peru | Manta (Quito), Ecuador | Fuerte Amador, Panama | Panama Canal, Panama | Georgetown, Grand Cayman, Cayman Islands | Fort Lauderdale (Port Everglades)
Zaandam

16-day South America Passage departing from San Antonio, Chile

Holland America Line
Zaandam
Ports of Call: San Antonio, Chile | Puerto Montt, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Montevideo, Uruguay | Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil
Zaandam

16-day South America Passage departing from Rio de Janeiro, Brazil

Holland America Line
Zaandam
Ports of Call: Rio de Janeiro, Brazil | Punta del Este, Uruguay | Buenos Aires, Argentina | Montevideo, Uruguay | Stanley, Falkland Islands | Ushuaia, Argentina | Punta Arenas, Chile | Amalia (Skua) Glacier, Chile | Puerto Montt, Chile | San Antonio, Chile
Zaandam

19-day Inca Discovery departing from San Diego, California

Holland America Line
Zaandam
Ports of Call: San Diego, California | Manzanillo, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Coquimbo (La Serena), Chile | San Antonio, Chile
Zaandam

20-day Inca And Panama Canal Discovery departing from San Antonio, Chile

Holland America Line
Zaandam
Ports of Call: San Antonio, Chile | Coquimbo (La Serena), Chile | General San Martin, Peru | Callao (Lima), Peru | Salaverry (Trujillo), Peru | Guayaquil (Quito), Ecuador | Manta (Quito), Ecuador | Fuerte Amador, Panama | Panama Canal, Panama | Port of Oranjestad, Aruba, Caribbean | Willemstad, Curacao | Kralendijk, Bonaire, Dutch Antilles | Fort Lauderdale (Port Everglades)
Zaandam

22-day South America & Antarctica departing from San Antonio, Chile

Holland America Line
Zaandam
Ports of Call: San Antonio, Chile | Puerto Montt, Chile | Castro, Chile | Puerto Chacabuco, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Puerto Madryn, Argentina | Montevideo, Uruguay | Buenos Aires, Argentina
Zaandam

22-day South America & Antarctica departing from Buenos Aires, Argentina

Holland America Line
Zaandam
Ports of Call: Buenos Aires, Argentina | Montevideo, Uruguay | Puerto Madryn, Argentina | Stanley, Falkland Islands | Ushuaia, Argentina | Punta Arenas, Chile | Amalia (Skua) Glacier, Chile | Puerto Chacabuco, Chile | Castro, Chile | Puerto Montt, Chile | San Antonio, Chile
Zaandam

23-day Inca Discovery departing from Vancouver, British Columbia

Holland America Line
Zaandam
Ports of Call: Vancouver, British Columbia | Santa Barbara, California | San Diego, California | Manzanillo, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Coquimbo (La Serena), Chile | San Antonio, Chile
Zaandam

24-day Inca Discovery departing from Seattle, Washington

Holland America Line
Zaandam
Ports of Call: Seattle, Washington | Vancouver, British Columbia | Santa Barbara, California | San Diego, California | Manzanillo, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Coquimbo (La Serena), Chile | San Antonio, Chile
Zaandam

26-day Brazil & South America Passage departing from Buenos Aires, Argentina

Holland America Line
Zaandam
Ports of Call: Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil | Buzios, Brazil | Abraao, Ilha Grande, Brazil | Santos (Sao Paulo), Brazil | Porto Belo (Santa Catarina), Brazil | Montevideo, Uruguay | Stanley, Falkland Islands | Punta Arenas, Chile | Ushuaia, Argentina | Puerto Montt, Chile | San Antonio, Chile
Zaandam

28-day Incan Empires departing from San Diego, California

Holland America Line
Maasdam
Ports of Call: San Diego, California | Cabo San Lucas, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Fuerte Amador, Panama | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Manta (Quito), Ecuador | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Manzanillo, Mexico | Puerto Vallarta, Mexico
Maasdam

28-day Amazon Explorer departing from Fort Lauderdale (Port Everglades)

Holland America Line
Prinsendam
Ports of Call: Fort Lauderdale (Port Everglades) | Philipsburg, St. Maarten | Terre-de-haut, Guadeloupe | Bridgetown, Barbados | Devils Island, French Guiana | Macapa, Brazil | Santarem, Brazil | Boca da Valeria, Brazil | Manaus, Brazil | Parintins, Brazil | Alter do Chao, Brazil | Belem, Brazil | Scarborough, Tobago | St. Georges, Grenada, West Indies | Santo Domingo, Domincan Republic
Prinsendam

30-day Incan Empires departing from San Diego, California

Holland America Line
Volendam
Ports of Call: San Diego, California | Cabo San Lucas, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | General San Martin, Peru | Puntarenas, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Manzanillo, Mexico | Puerto Vallarta, Mexico
Volendam

30-day South America & Inca Discovery departing from Buenos Aires, Argentina

Holland America Line
Zaandam
Ports of Call: Buenos Aires, Argentina | Montevideo, Uruguay | Stanley, Falkland Islands | Punta Arenas, Chile | Ushuaia, Argentina | Puerto Montt, Chile | San Antonio, Chile | Coquimbo (La Serena), Chile | General San Martin, Peru | Callao (Lima), Peru | Salaverry (Trujillo), Peru | Manta (Quito), Ecuador | Fuerte Amador, Panama | Panama Canal, Panama | Georgetown, Grand Cayman, Cayman Islands | Fort Lauderdale (Port Everglades)
Zaandam

31-day Grand South America & Antarctica Voyage departing from Buenos Aires, Argentina

Holland America Line
Prinsendam
Ports of Call: Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil | Buzios, Brazil | Salvador, Brazil | Fortaleza, Brazil | Santarem, Brazil | Boca da Valeria, Brazil | Manaus, Brazil | Parintins, Brazil | Alter do Chao, Brazil | Devils Island, French Guiana | Bridgetown, Barbados | Roseau, Dominica | Road Town, Tortola, B.V.I. | Fort Lauderdale (Port Everglades)
Prinsendam

34-day Antarctica & Brazil Explorer departing from San Antonio, Chile

Holland America Line
Zaandam
Ports of Call: San Antonio, Chile | Puerto Montt, Chile | Castro, Chile | Puerto Chacabuco, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Puerto Madryn, Argentina | Montevideo, Uruguay | Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil | Buzios, Brazil | Abraao, Ilha Grande, Brazil | Santos (Sao Paulo), Brazil | Porto Belo (Santa Catarina), Brazil
Zaandam

34-day South America Inca & Panama Canal Discovery departing from Buenos Aires, Argentina

Holland America Line
Zaandam
Ports of Call: Buenos Aires, Argentina | Montevideo, Uruguay | Stanley, Falkland Islands | Punta Arenas, Chile | Ushuaia, Argentina | Puerto Montt, Chile | San Antonio, Chile | Coquimbo (La Serena), Chile | General San Martin, Peru | Callao (Lima), Peru | Salaverry (Trujillo), Peru | Guayaquil (Quito), Ecuador | Manta (Quito), Ecuador | Fuerte Amador, Panama | Panama Canal, Panama | Port of Oranjestad, Aruba, Caribbean | Willemstad, Curacao | Kralendijk, Bonaire, Dutch Antilles | Fort Lauderdale (Port Everglades)
Zaandam

35-day Grand South America & Antarctica Voyage departing from Buenos Aires, Argentina

Holland America Line
Prinsendam
Ports of Call: Buenos Aires, Argentina | Santos (Sao Paulo), Brazil | Ilhabela, Brazil | Rio de Janeiro, Brazil | Ilheus(Bahia), Brazil | Recife, Brazil | Fortaleza, Brazil | Belem, Brazil | Santarem, Brazil | Boca da Valeria, Brazil | Manaus, Brazil | Parintins, Brazil | Alter do Chao, Brazil | Devils Island, French Guiana | Bridgetown, Barbados | Port Elizabeth, Saint Vincent | Isla Margarita, Venezuela | Willemstad, Curacao | Port of Oranjestad, Aruba, Caribbean | Fort Lauderdale (Port Everglades)
Prinsendam

35-day Inca Discovery & South America departing from San Diego, California

Holland America Line
Zaandam
Ports of Call: San Diego, California | Manzanillo, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Coquimbo (La Serena), Chile | San Antonio, Chile | Puerto Montt, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Montevideo, Uruguay | Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil
Zaandam

37-day Grand South America & Antarctica Voyage departing from Fort Lauderdale (Port Everglades)

Holland America Line
Prinsendam
Ports of Call: Fort Lauderdale (Port Everglades) | Georgetown, Grand Cayman, Cayman Islands | Puerto Limon, Costa Rica | Panama Canal, Panama | Manta (Quito), Ecuador | Guayaquil (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | General San Martin, Peru | Coquimbo (La Serena), Chile | San Antonio, Chile | Robinson Crusoe Island, Chile | Castro, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Montevideo, Uruguay | Buenos Aires, Argentina
Prinsendam

39-day Inca Discovery & South America departing from Vancouver, British Columbia

Holland America Line
Zaandam
Ports of Call: Vancouver, British Columbia | Santa Barbara, California | San Diego, California | Manzanillo, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Coquimbo (La Serena), Chile | San Antonio, Chile | Puerto Montt, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Montevideo, Uruguay | Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil
Zaandam

40-day Inca Discovery & South America departing from Seattle, Washington

Holland America Line
Zaandam
Ports of Call: Seattle, Washington | Vancouver, British Columbia | Santa Barbara, California | San Diego, California | Manzanillo, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Coquimbo (La Serena), Chile | San Antonio, Chile | Puerto Montt, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Montevideo, Uruguay | Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil
Zaandam

42-day South America Odyssey departing from Buenos Aires, Argentina

Holland America Line
Zaandam
Ports of Call: Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil | Buzios, Brazil | Abraao, Ilha Grande, Brazil | Santos (Sao Paulo), Brazil | Porto Belo (Santa Catarina), Brazil | Montevideo, Uruguay | Stanley, Falkland Islands | Punta Arenas, Chile | Ushuaia, Argentina | Puerto Montt, Chile | San Antonio, Chile | Coquimbo (La Serena), Chile | General San Martin, Peru | Callao (Lima), Peru | Salaverry (Trujillo), Peru | Manta (Quito), Ecuador | Fuerte Amador, Panama | Panama Canal, Panama | Georgetown, Grand Cayman, Cayman Islands | Fort Lauderdale (Port Everglades)
Zaandam

45-day Grand South America & Antarctica Voyage departing from Fort Lauderdale (Port Everglades)

Holland America Line
Prinsendam
Ports of Call: Fort Lauderdale (Port Everglades) | Santa Marta, Colombia | San Blas Islands, Panama | Panama Canal, Panama | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Matarani, Peru | Iquique, Chile | Antofagasta, Chile | San Antonio, Chile | Robinson Crusoe Island, Chile | Castro, Chile | Puerto Chacabuco, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Grytviken, South Georgia | Stanley, Falkland Islands | Puerto Madryn, Argentina | Punta del Este, Uruguay | Montevideo, Uruguay | Buenos Aires, Argentina
Prinsendam

68-day Grand South America & Antarctica Voyage departing from Fort Lauderdale (Port Everglades)

Holland America Line
Prinsendam
Ports of Call: Fort Lauderdale (Port Everglades) | Georgetown, Grand Cayman, Cayman Islands | Puerto Limon, Costa Rica | Panama Canal, Panama | Manta (Quito), Ecuador | Guayaquil (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | General San Martin, Peru | Coquimbo (La Serena), Chile | San Antonio, Chile | Robinson Crusoe Island, Chile | Castro, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Stanley, Falkland Islands | Montevideo, Uruguay | Buenos Aires, Argentina | Punta del Este, Uruguay | Rio de Janeiro, Brazil | Buzios, Brazil | Salvador, Brazil | Fortaleza, Brazil | Santarem, Brazil | Boca da Valeria, Brazil | Manaus, Brazil | Parintins, Brazil | Alter do Chao, Brazil | Devils Island, French Guiana | Bridgetown, Barbados | Roseau, Dominica | Road Town, Tortola, B.V.I.
Prinsendam

80-day Grand South America & Antarctica Voyage departing from Fort Lauderdale (Port Everglades)

Holland America Line
Prinsendam
Ports of Call: Fort Lauderdale (Port Everglades) | Santa Marta, Colombia | San Blas Islands, Panama | Panama Canal, Panama | Fuerte Amador, Panama | Manta (Quito), Ecuador | Salaverry (Trujillo), Peru | Callao (Lima), Peru | Matarani, Peru | Iquique, Chile | Antofagasta, Chile | San Antonio, Chile | Robinson Crusoe Island, Chile | Castro, Chile | Puerto Chacabuco, Chile | Amalia (Skua) Glacier, Chile | Punta Arenas, Chile | Ushuaia, Argentina | Grytviken, South Georgia | Stanley, Falkland Islands | Puerto Madryn, Argentina | Punta del Este, Uruguay | Montevideo, Uruguay | Buenos Aires, Argentina | Santos (Sao Paulo), Brazil | Ilhabela, Brazil | Rio de Janeiro, Brazil | Ilheus(Bahia), Brazil | Recife, Brazil | Fortaleza, Brazil | Belem, Brazil | Santarem, Brazil | Boca da Valeria, Brazil | Manaus, Brazil | Parintins, Brazil | Alter do Chao, Brazil | Devils Island, French Guiana | Bridgetown, Barbados | Port Elizabeth, Saint Vincent | Isla Margarita, Venezuela | Willemstad, Curacao | Port of Oranjestad, Aruba, Caribbean
Prinsendam

*From prices are per person, based on double occupancy and are cruise only unless otherwise specified. A 3.08% surcharge will apply for payments by Amex. A surcharge may apply for other card payments. Cruise guru charges a fee of $110 per person for cancellations and charges other fees in addition to any fees charged by cruise lines. Cancellation fees of up to 100% apply. View all fees and charges. Your exact price depends on the day of departure, departure city, ship and cabin. All offers and prices are for selected dates, sailings and cabin categories only and are subject to availability. Conditions apply.