Panama Canal

Slice through Central America via the most famous canal in the world. With more than 900 species of birds, 10,000 species of plants, 1,350 plants and animals indigenous to the country and more species of mammals and amphibians than any other Central American country, Panama has one of the richest tropical environments on earth. Follow the footsteps of the conquistadors and immerse yourself in Panama's rich ecological and cultural diversity.

14-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Nieuw Amsterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Huatulco, Mexico | Puerto Vallarta, Mexico | San Diego, California
Nieuw Amsterdam

14-day Panama Canal departing from San Diego, California

Holland America Line
Westerdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Fort Lauderdale (Port Everglades)
Westerdam

15-day Panama Canal Holiday departing from San Diego, California

Holland America Line
Amsterdam
Ports of Call: San Diego, California | Cabo San Lucas, Mexico | Puerto Vallarta, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Amsterdam

15-day Panama Canal departing from Los Angeles, California

Holland America Line
Amsterdam
Ports of Call: Los Angeles, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Fort Lauderdale (Port Everglades)
Amsterdam

15-day Panama Canal departing from San Diego, California

Holland America Line
Maasdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Maasdam

15-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Volendam
Ports of Call: Fort Lauderdale (Port Everglades) | Half Moon Cay (Little San Salvador Island), Bahamas | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Huatulco, Mexico | Puerto Vallarta, Mexico | San Diego, California
Volendam

15-day Panama Canal departing from San Diego, California

Holland America Line
Volendam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Volendam

15-day Panama Canal departing from San Diego, California

Holland America Line
Volendam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Key West, Florida | Fort Lauderdale (Port Everglades)
Volendam

15-day Panama Canal departing from San Diego, California

Holland America Line
Volendam
Ports of Call: San Diego, California | Cabo San Lucas, Mexico | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Volendam

15-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Westerdam
Ports of Call: Fort Lauderdale (Port Everglades) | Half Moon Cay (Little San Salvador Island), Bahamas | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Cabo San Lucas, Mexico | San Diego, California
Westerdam

15-day Panama Canal departing from San Diego, California

Holland America Line
Westerdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Georgetown, Grand Cayman, Cayman Islands | Fort Lauderdale (Port Everglades)
Westerdam

15-day Panama Canal departing from San Diego, California

Holland America Line
Westerdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Westerdam

16-day Panama Canal departing from San Diego, California

Holland America Line
Oosterdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Port of Oranjestad, Aruba, Caribbean | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Oosterdam

16-day Panama Canal Holiday departing from Fort Lauderdale (Port Everglades)

Holland America Line
Volendam
Ports of Call: Fort Lauderdale (Port Everglades) | Willemstad, Curacao | Port of Oranjestad, Aruba, Caribbean | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Huatulco, Mexico | Puerto Vallarta, Mexico | San Diego, California
Volendam

17-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Amsterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Huatulco, Mexico | Cabo San Lucas, Mexico | San Francisco, California | Victoria, British Columbia | Seattle, Washington
Amsterdam

17-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Amsterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Huatulco, Mexico | Cabo San Lucas, Mexico | San Francisco, California | Victoria, British Columbia | Vancouver, British Columbia
Amsterdam

17-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Eurodam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Francisco, California
Eurodam

17-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Nieuw Amsterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Diego, California
Nieuw Amsterdam

17-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Oosterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Fuerte Amador, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | San Diego, California
Oosterdam

17-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Volendam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Francisco, California
Volendam

17-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Zaandam
Ports of Call: Fort Lauderdale (Port Everglades) | Willemstad, Curacao | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Diego, California
Zaandam

18-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Amsterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Huatulco, Mexico | Cabo San Lucas, Mexico | San Francisco, California | Victoria, British Columbia | Vancouver, British Columbia | Seattle, Washington
Amsterdam

18-day Panama Canal departing from San Diego, California

Holland America Line
Nieuw Amsterdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Manzanillo, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Port of Oranjestad, Aruba, Caribbean | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Nieuw Amsterdam

19-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Eurodam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Francisco, California | Vancouver, British Columbia
Eurodam

19-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Westerdam
Ports of Call: Fort Lauderdale (Port Everglades) | Half Moon Cay (Little San Salvador Island), Bahamas | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Cabo San Lucas, Mexico | San Diego, California | Victoria, British Columbia | Vancouver, British Columbia
Westerdam

20-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Eurodam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Francisco, California | Vancouver, British Columbia | Seattle, Washington
Eurodam

20-day Panama Canal departing from San Diego, California

Holland America Line
Maasdam
Ports of Call: San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Cartagena, Colombia | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades) | Charleston, South Carolina | Boston, Massachusetts
Maasdam

20-day Panama Canal departing from San Francisco, California

Holland America Line
Volendam
Ports of Call: San Francisco, California | San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Port of Oranjestad, Aruba, Caribbean | Willemstad, Curacao | Fort Lauderdale (Port Everglades)
Volendam

20-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Volendam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Francisco, California | Victoria, British Columbia | Vancouver, British Columbia
Volendam

21-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Nieuw Amsterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Diego, California | Victoria, British Columbia | Vancouver, British Columbia
Nieuw Amsterdam

21-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Oosterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Fuerte Amador, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | San Diego, California | Victoria, British Columbia | Vancouver, British Columbia
Oosterdam

22-day Panama Canal departing from Vancouver, British Columbia

Holland America Line
Nieuw Amsterdam
Ports of Call: Vancouver, British Columbia | Seattle, Washington | San Diego, California | Puerto Vallarta, Mexico | Manzanillo, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Port of Oranjestad, Aruba, Caribbean | Half Moon Cay (Little San Salvador Island), Bahamas | Fort Lauderdale (Port Everglades)
Nieuw Amsterdam

22-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Oosterdam
Ports of Call: Fort Lauderdale (Port Everglades) | Cartagena, Colombia | Panama Canal, Panama | Fuerte Amador, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | San Diego, California | Victoria, British Columbia | Vancouver, British Columbia | Seattle, Washington
Oosterdam

22-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Zaandam
Ports of Call: Fort Lauderdale (Port Everglades) | Willemstad, Curacao | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Diego, California | San Francisco, California | Vancouver, British Columbia
Zaandam

23-day Panama Canal departing from Vancouver, British Columbia

Holland America Line
Volendam
Ports of Call: Vancouver, British Columbia | San Francisco, California | San Diego, California | Puerto Vallarta, Mexico | Huatulco, Mexico | Puerto Chiapas, Mexico | Puerto Quetzal, Guatemala | Puerto Corinto, Nicaragua | Puerto Caldera, Costa Rica | Panama Canal, Panama | Port of Oranjestad, Aruba, Caribbean | Willemstad, Curacao | Fort Lauderdale (Port Everglades)
Volendam

23-day Panama Canal departing from Fort Lauderdale (Port Everglades)

Holland America Line
Zaandam
Ports of Call: Fort Lauderdale (Port Everglades) | Willemstad, Curacao | Panama Canal, Panama | Puerto Caldera, Costa Rica | Puerto Corinto, Nicaragua | Puerto Quetzal, Guatemala | Puerto Chiapas, Mexico | Huatulco, Mexico | Manzanillo, Mexico | Puerto Vallarta, Mexico | Cabo San Lucas, Mexico | San Diego, California | San Francisco, California | Vancouver, British Columbia | Seattle, Washington
Zaandam

*From prices are per person, based on double occupancy and are cruise only unless otherwise specified. A 3.08% surcharge will apply for payments by Amex. A surcharge may apply for other card payments. Cruise guru charges a fee of $110 per person for cancellations and charges other fees in addition to any fees charged by cruise lines. Cancellation fees of up to 100% apply. View all fees and charges. Your exact price depends on the day of departure, departure city, ship and cabin. All offers and prices are for selected dates, sailings and cabin categories only and are subject to availability. Conditions apply.